ChloroquineV1, Main, Exploration, bibRecord, 003615

Amiodarone lung toxicity: A human and experimental study

Identifieur interne : 003615 ( Main/Exploration ); précédent : 003614; suivant : 003616

Amiodarone lung toxicity: A human and experimental study

Auteurs : F. R. Costa-Jussà [Royaume-Uni] ; B. Corrin [Royaume-Uni] ; J. M. Jacobs [Royaume-Uni]

Source :

The Journal of Pathology [ 0022-3417 ] ; 1984-10.

RBID : ISTEX:6552EBD63C35D6F3F9F58A92A188369EF76933BC

English descriptors

Teeft :
- Alveolus, Amer heart, Amiodarone, Amiodarone lung toxicity, Amiodarone pneumonitis, Amiodarone toxicity, Anorectic drug, Biopsy, Clinical details, Corrin, Cultured macrophages, Cultured neurons, Dense inclusions, Dosing, Electron microscopy, Endogenous lipid pneumonia, Eosin, Eosinophilic bronchiolitis, Experimental study, Foamy macrophages, Haematoxylin, Histiocytosis, Inclusion, Interstitial, Interstitial fibrosis, Interstitial oedema, Iprindole, Lamellated, Lamellated bodies, Lamellated structures, Lipid, Lipid pneumonia, Lysosomal, Lysosome, Macrophage, Neuropathy, Open lung biopsy, Open squares, Phospholipase, Phospholipid, Plastic sections, Pneumocytes, Pneumonitis, Pulmonary histiocytosis, Queen square, Similar inclusions, Solid squares, Standard deviations, Toxicity.

Abstract

This paper describes the pathology of pulmonary histiocytosis developing in a patient treated with amiodarone, and reports comparable changes in the lungs of rats and mice to which this drug had been administered. Ultrastructural studies indicate that the experimental lung changes are similar to those produced by iprindole and chlorphentermine. The patient also displayed focal necroses and an eosinophilic bronchiolitis: these may represent further effects of amiodarone on the lung.

Url:

https://api.istex.fr/ark:/67375/WNG-XH2DJZZ4-K/fulltext.pdf

DOI: 10.1002/path.1711440202

Affiliations:

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to stream Istex, to step Corpus: 001917
to stream Istex, to step Curation: 001917
to stream Istex, to step Checkpoint: 002375
to stream Main, to step Merge: 003689
to stream Main, to step Curation: 003615

Le document en format XML

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<author><name sortKey="Corrin, B" sort="Corrin, B" uniqKey="Corrin B" first="B." last="Corrin">B. Corrin</name>
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<term>Amer heart</term>
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<term>Amiodarone lung toxicity</term>
<term>Amiodarone pneumonitis</term>
<term>Amiodarone toxicity</term>
<term>Anorectic drug</term>
<term>Biopsy</term>
<term>Clinical details</term>
<term>Corrin</term>
<term>Cultured macrophages</term>
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<term>Dense inclusions</term>
<term>Dosing</term>
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<term>Eosin</term>
<term>Eosinophilic bronchiolitis</term>
<term>Experimental study</term>
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<term>Haematoxylin</term>
<term>Histiocytosis</term>
<term>Inclusion</term>
<term>Interstitial</term>
<term>Interstitial fibrosis</term>
<term>Interstitial oedema</term>
<term>Iprindole</term>
<term>Lamellated</term>
<term>Lamellated bodies</term>
<term>Lamellated structures</term>
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<term>Lipid pneumonia</term>
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<term>Lysosome</term>
<term>Macrophage</term>
<term>Neuropathy</term>
<term>Open lung biopsy</term>
<term>Open squares</term>
<term>Phospholipase</term>
<term>Phospholipid</term>
<term>Plastic sections</term>
<term>Pneumocytes</term>
<term>Pneumonitis</term>
<term>Pulmonary histiocytosis</term>
<term>Queen square</term>
<term>Similar inclusions</term>
<term>Solid squares</term>
<term>Standard deviations</term>
<term>Toxicity</term>
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<front><div type="abstract" xml:lang="en">This paper describes the pathology of pulmonary histiocytosis developing in a patient treated with amiodarone, and reports comparable changes in the lungs of rats and mice to which this drug had been administered. Ultrastructural studies indicate that the experimental lung changes are similar to those produced by iprindole and chlorphentermine. The patient also displayed focal necroses and an eosinophilic bronchiolitis: these may represent further effects of amiodarone on the lung.</div>
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Amiodarone lung toxicity: A human and experimental study

Amiodarone lung toxicity: A human and experimental study

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri